Applicants
Principal Investigators are faculty whose principal appointment is at Brown University specifically, investigators who are covered by the Brown University IP policy and have an obligation to assign IP to Brown University are eligible to apply. Emeritus, adjunct, and visiting faculty, as well as post docs, are not eligible to lead projects, but may be included on the research team.
In addition, investigators employed by Brown-affiliated hospital partners (Care New England and Lifespan) who have a primary academic appointment at Brown University shall be eligible so long as their application includes a letter of support from their research administration office*. The letter needs to state (a) that the project is approved for inclusion in this program, (b) that the hospital partner is willing to accept the revenue sharing provisions for this program; and (c) that the hospital partner agrees to waive indirect fees.
Only one pre-proposal per applicant will be accepted per cycle.
Lifespan and Care New England
- Lifespan investigators should seek approval letters from the Vice President of Research Administration (current contact Michael Henderson mhenderson1@lifespan.org)
- Care New England investigators should obtain a letter from Colleen Ramos, Vice President Finance, Women & Infants Hospital at cramos@carene.org with a copy to Susan Senerchia at ssenerchia@wihri.org.
Activities Eligible for Funding
The focus of this program is the biomedical sciences, specifically, identification and development of therapeutics, diagnostics or medical devices. Examples of translational projects eligible for funding include but are not limited to:
- Identification and/or chemical optimization of small molecule leads
- Development of therapeutic or diagnostic antibodies or other biologics
- Testing of lead molecules or biologics in cell-based and/or animal models of disease to confirm their therapeutic or diagnostic relevance
- Identification and validation of a biomarker for efficacy or profiling
- Development and/or testing of a diagnostic or medical device prototype
In many cases the work may be outsourced to contract research organizations (CROs), for instance medicinal chemistry services or in vivo efficacy models or nonclinical studies. BBII, with input from the Principal Investigator will identify suitable CRO partners, negotiate contracts and manage outsourced projects.